Peter Keightley     Evolutionary Genetics University of Edinburgh

Software Resources

MCALIGN: alignment of noncoding DNA sequences based on explicit models of indel evolution.

MLGENOMEU: Estimation of mutation parameters from mutation accumulation experiments.

DFE-alpha version 2.15. Inference of the distribution of fitness effects of new mutations and frequency of adaptive molecular evolution.

Estimate the unfolded site frequency spectrum version 1.01. Uses the maximum likelihood method described by Keightley et al. (2016) [PDF].