Peter Keightley     Evolutionary Genetics University of Edinburgh


Software Resources



MCALIGN: alignment of noncoding DNA sequences based on explicit models of indel evolution.



MLGENOMEU: Estimation of mutation parameters from mutation accumulation experiments.



DFE-alpha version 2.16. Inference of the distribution of fitness effects of new mutations and frequency of adaptive molecular evolution.



est-sfs: estimate the unfolded SFS and ancestral states at polymorphic sites. Uses the method of Keightley and Jackson (2018).



Superseded software to estimate the unfolded SFS. Uses the method of Keightley et al (2016).